A late-breaking abstract (LBA 2) that will be presented later this morning as an oral presentation identified new genes associated with variations in sleep duration. The genome-wide association study involved 2,200 people in Finland; they were characterized for sleep length per night and evaluated for depressive symptoms and variation in mood.
The researchers found several new genes and variants that showed statistically significant association with total sleep length. Analysis also showed that sleep length and seasonal changes in mood share common molecular genes and pathways. This suggests that sleep disturbances and mood disorders may share common genetic components.
You can read the abstract in the final program.
Showing posts with label sleep duration. Show all posts
Showing posts with label sleep duration. Show all posts
Thursday, June 11, 2009
Sleep & Weight Gain
Two studies that will be presented later this morning as oral presentations shed light on the associations between sleep and weight gain.
One study (#0981) used data from 1,797 twins with an average age of 37 years to show that body mass index (BMI) varied as a function of habitual sleep duration. Results show that twins who slept between 7 and 8.9 hours each night had a lower mean BMI (25.0 kg/m2) compared with those who regularly slept either more (25.2 kg/m2) or less (26.4 kg/m2) per night. The findings remained significant even after careful adjustment for genetics and shared environment.
Analyzing data from the Sleep Heart Health Study, another study (#0515) suggests that there is a positive association between the severity of obstructive sleep apnea and subsequent change in BMI over approximately five years. The study involved 3,001 people with an average age of 62 years. Compared with participants who did not have sleep apnea, individuals with baseline moderate to severe sleep apnea had a mean change in BMI of 0.52 kg/m2; those with mild sleep apnea had a BMI change of 0.22 kg/m2. The association was significant despite adjustments for age, gender and race.
You can download the SLEEP 2009 abstract supplement as an 11 MB file in PDF format.
One study (#0981) used data from 1,797 twins with an average age of 37 years to show that body mass index (BMI) varied as a function of habitual sleep duration. Results show that twins who slept between 7 and 8.9 hours each night had a lower mean BMI (25.0 kg/m2) compared with those who regularly slept either more (25.2 kg/m2) or less (26.4 kg/m2) per night. The findings remained significant even after careful adjustment for genetics and shared environment.
Analyzing data from the Sleep Heart Health Study, another study (#0515) suggests that there is a positive association between the severity of obstructive sleep apnea and subsequent change in BMI over approximately five years. The study involved 3,001 people with an average age of 62 years. Compared with participants who did not have sleep apnea, individuals with baseline moderate to severe sleep apnea had a mean change in BMI of 0.52 kg/m2; those with mild sleep apnea had a BMI change of 0.22 kg/m2. The association was significant despite adjustments for age, gender and race.
You can download the SLEEP 2009 abstract supplement as an 11 MB file in PDF format.
Wednesday, June 10, 2009
Sleepless and Stressed
A study (#1268) being presented this morning as a poster reports that there is a bidirectional relationship between stress and poor sleep.
Results show that higher habitual stress is associated with reported shorter sleep duration, poorer sleep quality, and daytime functioning impairments. Conversely, daytime functioning impairments and shorter sleep duration demonstrated a predictive relationship with habitual stress complaints.
In February the Sleep Education Blog reported that stress related to the struggling economy can have a negative impact on sleep. On SleepEducation.com the American Academy of Sleep Medicine describes how job stress can affect sleep.
You can download the SLEEP 2009 abstract supplement as an 11 MB file in PDF format.
Results show that higher habitual stress is associated with reported shorter sleep duration, poorer sleep quality, and daytime functioning impairments. Conversely, daytime functioning impairments and shorter sleep duration demonstrated a predictive relationship with habitual stress complaints.
In February the Sleep Education Blog reported that stress related to the struggling economy can have a negative impact on sleep. On SleepEducation.com the American Academy of Sleep Medicine describes how job stress can affect sleep.
You can download the SLEEP 2009 abstract supplement as an 11 MB file in PDF format.
Sleep & Growing Older
Three studies that will be presented later this morning as posters shed light on issues related to sleep in older adults.
A study (#0363) involving Sleep Heart Health Study participants used direct measures of sleep fragmentation to show that increases in specific sleep stage transitions during the night are associated with higher mortality risk. This association was found in middle-aged and older adults who had more objectively measured wake to non-rapid eye movement (NREM) sleep transitions per hour of sleep, and in participants who had more NREM to wake transitions. Over the average follow-up period of eight years, 854 of the 5,614 participants died (15.2 percent).
A study (#0373) involving a national sample of older Americans shows that more than 55 percent reported sleeping for an average of seven hours or less per night during the past month. But only 18 percent reported that they “often” or “almost always” feel “unrested during the day.” The average age of the 1,570 participants was 71.9 years.
Another study (#0420) reports that older adults (between 59 and 82 years of age) showed more resiliency to total sleep deprivation than younger adults (between 19 and 38 years of age) on a range of measures of cognitive performance. Participants completed three cognitive tasks before and after sleep deprivation lasting 12 hours and 36 hours. For all three tasks, young adults significantly declined during total sleep deprivation while older adults did not change significantly.
You can download the SLEEP 2009 abstract supplement as an 11 MB file in PDF format.
A study (#0363) involving Sleep Heart Health Study participants used direct measures of sleep fragmentation to show that increases in specific sleep stage transitions during the night are associated with higher mortality risk. This association was found in middle-aged and older adults who had more objectively measured wake to non-rapid eye movement (NREM) sleep transitions per hour of sleep, and in participants who had more NREM to wake transitions. Over the average follow-up period of eight years, 854 of the 5,614 participants died (15.2 percent).
A study (#0373) involving a national sample of older Americans shows that more than 55 percent reported sleeping for an average of seven hours or less per night during the past month. But only 18 percent reported that they “often” or “almost always” feel “unrested during the day.” The average age of the 1,570 participants was 71.9 years.
Another study (#0420) reports that older adults (between 59 and 82 years of age) showed more resiliency to total sleep deprivation than younger adults (between 19 and 38 years of age) on a range of measures of cognitive performance. Participants completed three cognitive tasks before and after sleep deprivation lasting 12 hours and 36 hours. For all three tasks, young adults significantly declined during total sleep deprivation while older adults did not change significantly.
You can download the SLEEP 2009 abstract supplement as an 11 MB file in PDF format.
Tuesday, June 9, 2009
Teen Bedtimes Associated with Suicide, Depression & Grades
Two studies being presented as posters later this morning examine the negative impact of late bedtimes on teens.
One study (#1064) suggests that parental-mandated bedtimes could help protect teens from depression and suicidal thoughts by lengthening sleep duration. Results show that adolescents with parental-mandated bedtimes at midnight or later were 25 percent more likely (adjusted odds ratio 1.25) to suffer from depression and 20 percent more likely (adjusted odds ratio 1.20) to have suicidal ideation compared with adolescents who had parental-mandated bedtimes of 10 p.m. or earlier. Multivariate models show that sleep duration may have acted as a mediator of these associations; thus short sleep may be a risk factor for depression and suicidal ideation.
Another study (#0161) shows that being a “night owl” or “evening type” – preferring to go to bed late at night and wake up later in the day – is associated with lower academic performance in college and a decline in academic performance from college to high school. Results indicate that evening types had significantly lower first year college GPA (2.84) than “morning types” and “intermediate types” (3.18). They also slept on average 41 minutes less on school nights. For all students, “sleep hygiene” was related to academic performance.
You can download the SLEEP 2009 abstract supplement as an 11 MB file in PDF format.
One study (#1064) suggests that parental-mandated bedtimes could help protect teens from depression and suicidal thoughts by lengthening sleep duration. Results show that adolescents with parental-mandated bedtimes at midnight or later were 25 percent more likely (adjusted odds ratio 1.25) to suffer from depression and 20 percent more likely (adjusted odds ratio 1.20) to have suicidal ideation compared with adolescents who had parental-mandated bedtimes of 10 p.m. or earlier. Multivariate models show that sleep duration may have acted as a mediator of these associations; thus short sleep may be a risk factor for depression and suicidal ideation.
Another study (#0161) shows that being a “night owl” or “evening type” – preferring to go to bed late at night and wake up later in the day – is associated with lower academic performance in college and a decline in academic performance from college to high school. Results indicate that evening types had significantly lower first year college GPA (2.84) than “morning types” and “intermediate types” (3.18). They also slept on average 41 minutes less on school nights. For all students, “sleep hygiene” was related to academic performance.
You can download the SLEEP 2009 abstract supplement as an 11 MB file in PDF format.
Wired Teens, Sleep Loss & Obesity
A study (#0320) being presented as a poster later this morning shows that excessive use of technology by children and teens may be related to both sleep loss and obesity. The study involved 320 students between the ages of 10 and 18 years. Results show that children who had more hours of “screen time” (TV, Internet, computer and video games) got less sleep and consumed more caffeine. Having a shorter sleep duration was associated with a higher body mass index (BMI).
A similar study (#0200) was presented yesterday and published in the June issue of the journal Pediatrics. Read a summary of the study on the Sleep Education Blog.
You can download the SLEEP 2009 abstract supplement as an 11 MB file in PDF format.
A similar study (#0200) was presented yesterday and published in the June issue of the journal Pediatrics. Read a summary of the study on the Sleep Education Blog.
You can download the SLEEP 2009 abstract supplement as an 11 MB file in PDF format.
Monday, June 8, 2009
Sleep Extension Improves Performance, Mood of Stanford Tennis Players
A small study (#0469) being presented later this morning as a poster adds to the growing body of evidence showing that sleep extension can improve athletic performance.
The study involved five members of the Stanford women’s tennis team. Extending their sleep to 10 hours each night was associated with significant improvements in measures of athletic performance.
They executed a faster sprinting drill and increased their hitting accuracy. Their daytime sleepiness and fatigue also decreased, and their vigor improved.
The results are consistent with similar studies previously conducted with Stanford athletes in other sports. An abstract presented at SLEEP 2008 involved men and women on the Stanford swimming teams.
You can download the SLEEP 2009 abstract supplement as an 11 MB file in PDF format.
Sleep, Obesity & Diabetes in Black and White
Three studies being presented later this morning as posters examine the relationship between race and sleep.
One study (#0463) reports that race significantly influences the risk of obesity conferred by short sleep duration, with blacks having a higher risk than whites. Results show that the prevalence of both short sleep and obesity was higher in black Americans than in white Americans.
Another study (#0459) used the same sample to show that both short and long sleepers are at great risk for diabetes. The prevalence of diabetes was 12 percent for blacks and eight percent for whites.
A third study (#1197) shows that whites were more likely to report having excessive daytime sleepiness more than five days per month, but African Americans had a significantly higher risk of daytime sleepiness using the Epworth Sleepiness Scale.
You can download the SLEEP 2009 abstract supplement as an 11 MB file in PDF format.
One study (#0463) reports that race significantly influences the risk of obesity conferred by short sleep duration, with blacks having a higher risk than whites. Results show that the prevalence of both short sleep and obesity was higher in black Americans than in white Americans.
Another study (#0459) used the same sample to show that both short and long sleepers are at great risk for diabetes. The prevalence of diabetes was 12 percent for blacks and eight percent for whites.
A third study (#1197) shows that whites were more likely to report having excessive daytime sleepiness more than five days per month, but African Americans had a significantly higher risk of daytime sleepiness using the Epworth Sleepiness Scale.
You can download the SLEEP 2009 abstract supplement as an 11 MB file in PDF format.
Insomnia Linked to Mortality
A study (#0868) being presented later this morning as a poster reports that insomnia with short sleep duration in men is associated with increased mortality. In women with insomnia and short sleep duration, the mortality risk was increased but not statistically significant.
In the April 1 issue of the journal SLEEP, the same research team also published a study showing that chronic insomnia with objectively measured short sleep time is an independent and clinically significant risk factor for hypertension. Read an AASM press release about the study.
You can download the SLEEP 2009 abstract supplement as an 11 MB file in PDF format.
In the April 1 issue of the journal SLEEP, the same research team also published a study showing that chronic insomnia with objectively measured short sleep time is an independent and clinically significant risk factor for hypertension. Read an AASM press release about the study.
You can download the SLEEP 2009 abstract supplement as an 11 MB file in PDF format.
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